News & Updates

Stay up-to-date with the latest news from research, product development and clinical studies

Fragmentomics and MRD: A New Frontier in Cancer Detection

Fragmentomics and MRD: A New Frontier in Cancer Detection

September 17, 2025 Evangelos Theodorakis, Bioinformatician and Data Scientist

In recent years, researchers have realized that circulating cell-free DNA (cfDNA) in the blood carries far more information than just mutations. cfDNA fragments reflect the way chromatin is packaged and cut during apoptosis.

Bioinformatics ctDNA Fragmentomics Liquid Biopsy MRD
MRD in Lymphoma and Hodgkin Lymphoma: The Role of Liquid Biopsy and ctDNA Analysis

MRD in Lymphoma and Hodgkin Lymphoma: The Role of Liquid Biopsy and ctDNA Analysis

August 06, 2025 Lisa Baum, PhD, Bioinformatician and Data Scientist

Lymphoma is a type of cancer that originates from lymphocytes, which are white blood cells that help fight infections as part of the immune response. There are two main types of lymphoma: Hodgkin lymphoma (HL) and Non-Hodgkin lymphoma (NHL).

Cancer Diagnostics ctDNA Liquid Biopsy Lymphoma MRD
MRD Detection Methodology in Solid Tumors

MRD Detection Methodology in Solid Tumors

June 20, 2025 Lisa Baum, PhD, Bioinformatician and Data Scientist

Assessment of minimal residual disease (MRD) is becoming an increasingly important tool for early detection of tumor recurrence and guiding treatment decisions in the management of solid tumors.

Liquid Biopsy MRD NGS Oncology Solid Tumors
Challenges and Advances in Determining MRD in Solid Tumors

Challenges and Advances in Determining MRD in Solid Tumors

May 28, 2025 Lisa Baum, PhD, Bioinformatician and Data Scientist

Minimal residual disease (MRD) refers to a small number of cancer cells that can remain in a patient’s body after treatment, potentially leading to relapse.

ctDNA Liquid Biopsy MRD NGS Solid Tumors
Liquid Biopsy Diagnostics

Liquid Biopsy Diagnostics

May 07, 2025 Sven Borchmann, MD/PhD, Founder & Managing Director

In May, we kicked off our latest research project, “Fragmentomics by LIQOMICS”, supported with approx. €370,000 in funding from the state of North Rhine-Westphalia.

Bioinformatics ctDNA Liquid Biopsy MRD Research Project
Minimal Residual Disease (MRD) in Liquid Biopsies

Minimal Residual Disease (MRD) in Liquid Biopsies

May 05, 2025 Lisa Baum, PhD, Bioinformatician and Data Scientist

In our last article, we explored the importance of minimal residual disease (MRD) in cancer treatment and highlighted its role in predicting relapse and guiding personalized therapy.

Cancer Diagnostics ctDNA Liquid Biopsy MRD NGS
Liquid Biopsies in Solid Tumors and MRD Testing

Liquid Biopsies in Solid Tumors and MRD Testing

April 22, 2025 Lisa Baum, PhD, Bioinformatician and Data Scientist

Solid tumors are abnormal masses of tissue that develop when cells grow uncontrollably and do not contain cysts or liquid areas (NIH, national cancer institute). They can be benign (non-cancerous) or malignant (cancerous). Common types of solid tumors include carcinomas, sarcomas, and lymphomas. Solid tumors can occur in various parts of the body, such as the breast, lung, prostate, colon, and skin.

ctDNA Liquid Biopsy MRD Oncology Solid Tumors
Minimal Residual Disease (MRD) in Cancer

Minimal Residual Disease (MRD) in Cancer

March 17, 2025 Lisa Baum, PhD, Bioinformatician and Data Scientist

In cancer treatment, early and accurate diagnosis is only part of the challenge. Equally important is ensuring that a patient remains cancer-free after initial therapy, since cancer has a tendency to return if any malignant cells remain.

ctDNA Lymphoma MRD Oncology Precision Medicine
Fragmentomics by LIQOMICS

Fragmentomics by LIQOMICS

January 23, 2025 Sven Borchmann, MD/PhD, Founder & Managing Director

We are thrilled to announce that our project, Fragmentomics by LIQOMICS, has been selected as one of only 4 projects that will be supported as part of the prestigious funding program ZukunftBIO.NRW.

ctDNA Fragmentomics Liquid Biopsy Lymphoma Research Project
Circulating Tumor DNA (ctDNA)

Circulating Tumor DNA (ctDNA)

January 09, 2025 Lisa Baum, PhD, Bioinformatician and Data Scientist

In our last article, we introduced the basics of circulating cell-free DNA (cfDNA), its release and clearance mechanisms, and its central role in cancer diagnostics. Now that you are familiar with the fundamental concepts of cfDNA, this follow-up dives deeper into its biological significance.

Cancer Diagnostics ctDNA Liquid Biopsy NGS Oncology
LymphoVista HL assay at the ASH 2024, MRD in Hodgkin Lymphoma

LymphoVista HL assay at the ASH 2024, MRD in Hodgkin Lymphoma

December 18, 2024 Sven Borchmann, MD/PhD, Founder & Managing Director

LIQOMICS, a leading innovator in cancer diagnostics, is thrilled to announce the presentation of data on the LymphoVista HL assay at the 2024 Annual Meeting of the American Society of Hematology (ASH) in San Diego.

Clinical Trials ctDNA Hodgkin Lymphoma Liquid Biopsy MRD
Cancer Diagnostics through ctDNA

Cancer Diagnostics through ctDNA

December 09, 2024 Lisa Baum, PhD, Bioinformatician and Data Scientist

Recent advances in cancer research have significantly expanded our understanding of the complex biology of tumors. Particularly promising is the study of circulating tumor DNA (ctDNA)—tiny, cell-free DNA fragments released into the bloodstream by cancer cells.

Cancer Diagnostics ctDNA Liquid Biopsy Molecular Biology MRD
Exciting Updates for the Hematology and Oncology Community

Exciting Updates for the Hematology and Oncology Community

October 18, 2024 Sven Borchmann, MD/PhD, Founder & Managing Director

We’re thrilled that next week, from October 26-28, 2024, the highly anticipated 13th International Symposium on Hodgkin Lymphoma (ISHL 13) will take place in Cologne.

Cancer Diagnostics Conferences Hodgkin Lymphoma MRD Oncology
Understanding Minimal Residual Disease (MRD)

Understanding Minimal Residual Disease (MRD)

September 17, 2024 Maximilian Schiener, PhD, Laboratory, Scientific and Quality Manager

The analysis of minimal residual disease (MRD) using circulating tumor DNA (ctDNA) is gaining increasing importance as a precise tool for monitoring cancer during and after treatment. But what do MRD values actually mean – and how can they be translated into something more tangible?

ctDNA Genomics Liquid Biopsy MRD Oncology
Lookout for Collaborators

Lookout for Collaborators

March 15, 2024 Sven Borchmann, MD/PhD, Founder & Managing Director

We are always on the lookout for collaborators.

Cancer Research Collaborations ctDNA Liquid Biopsy MRD