MRD Diagnostics

Our minimal residual disease testing platform enables the precise detection and monitoring of remaining cancer cells after therapy.

What is MRD Diagnostics?

MRD (Minimal Residual Disease) refers to the smallest amounts of cancer cells that may persist in the body after treatment. These cells are often undetectable with conventional imaging methods but can be revealed through minimal residual disease MRD testing using highly sensitive ctDNA assays.

Through continuous minimal residual disease monitoring, clinicians can detect relapse months before it becomes visible on imaging and tailor therapeutic strategies accordingly.

Early Detection

Detect disease recurrence months before it becomes visible through imaging methods, enabling early intervention

Therapy Monitoring

Continuous minimal residual disease monitoring during treatment provides dynamic insights into therapy response and resistance

Risk Stratification

Assess individual relapse risk with precision to personalize follow-up and post-treatment care

Available Tests

Available

LymphoVista

B-Cell Lymphomas

ctDNA test for all B-cell lymphomas including DLBCL, follicular lymphoma, mantle cell lymphoma, marginal zone lymphoma, Burkitt lymphoma, and CNS lymphoma.

Sensitivity (LoD): 6.69 × 10⁻⁶
Clinical Validation: 326 samples, 88 patients, prognosis assessment possible for relapsed B-cell lymphoma 1
Cost: €2,965 (Initial) / €1,985 (Follow-up)
Available

LymphoVista HL

Hodgkin Lymphoma

Specifically developed for Hodgkin lymphoma with a modified gene spectrum optimized for HL.

Sensitivity (LoD): 6.54 × 10⁻⁶
Clinical Validation: HD21 study, 50 months follow-up, prognosis assessment possible after 2 cycles of chemotherapy 2
Cost: €2,965 (Initial) / €1,985 (Follow-up)

CancerVista - Solid Tumors

In Development

Currently available for research use only (RUO)

LIQOMICS is expanding its portfolio with minimal residual disease testing solutions for solid tumors. The CancerVista pipeline aims to enable minimal residual disease monitoring and therapy evaluation for a broad range of cancers.

Planned Tumor Types:

Lung Cancer

NSCLC & SCLC

Breast Cancer

All subtypes

Colorectal Cancer

Colorectal carcinoma

Prostate Cancer

Prostate carcinoma

Ovarian Cancer

Ovarian carcinoma

Pancreatic Cancer

Pancreatic carcinoma

Glioblastoma

CNS tumors

Additional

Additional tumor types in planning

Clinical Applications

After Primary Therapy

Perform minimal residual disease testing after completion of primary therapy to assess treatment response and identify patients at risk of relapse.

During Therapy

Use minimal residual disease MRD testing to monitor disease burden and detect resistance or treatment failure in real time.

Follow-up Care

Enable continuous minimal residual disease monitoring for early relapse detection, often months before imaging results show recurrence.

Clinical Studies

Support clinical research with precise MRD endpoints for therapy evaluation, survival analysis, and personalized medicine approaches.

Vista Technology

Our proprietary Vista technology allows ultra-sensitive ctDNA analysis with tumor-specific gene panels. It detects even the smallest traces of tumor DNA with exceptional accuracy and reproducibility.

High Sensitivity

Detection limits up to 6.69 × 10⁻⁶ for precise MRD detection

Tumor-Specific Panels

Optimized for diverse hematologic and solid tumors

Clinically Validated

Supported by multi-center studies with prognostic significance

RilibÄK Compliant

Adheres to German quality assurance standards

References

1 Schleifenbaum et al. Presentation at European Hematology Association (EHA) Annual Meeting 2024

2 Mattlener et al. Presentation at American Society of Hematology (ASH) Annual Meeting 2024

Interested in MRD Diagnostics?

Contact us for more information about our minimal residual disease testing services or to order one of our available assays.