We provide combined genotyping and MRD assays for research purposes across all cancers. Our particular expertise is in lymphomas and hematological cancers. Beyond our standard assays we can integrate individual, exploratory features in collaboration projects. Please contact us for more information.
A blood sample is sent to Liqomics and analyzed to identify tumor variants in the circulating tumor DNA to genotype the tumor and identify variants to track over time for MRD detection.
Blood samples are sent to Liqomics and the identified tumor variants identifying each tumor are used to track minimal residual disease (MRD) at extremely high accuracy.
Blood samples are sent to Liqomics for monitoring of patients in remission. An increase in MRD can trigger a new treatment much earlier than a radiological relapse.
We have a highly sensitive combined MRD and genotyping assay for all lymphomas readily available. Assays for solid tumors such as lung cancer, gynecological tumors or pancreatic cancer can easily be designed for individual projects, leveraging our unique platform. Specific genomic targets that are of interest for your project can easily be included. Please contact us for more information.
We have a highly sensitive combined MRD and genotyping assay for all lymphomas readily available. Assays for solid tumors such as lung cancer, gynecological tumors or pancreatic cancer can easily be designed for individual projects, leveraging our unique platform. Specific genomic targets that are of interest for your project can easily be included. Please contact us for more information.
A blood sample is sent to Liqomics and analyzed to identify tumor variants in the circulating tumor DNA to genotype the tumor and identify variants to track over time for MRD detection.
Blood samples are sent to Liqomics and the identified tumor variants identifying each tumor are used to track minimal residual disease (MRD) at extremely high accuracy.
Blood samples are sent to Liqomics for monitoring of patients in remission. An increase in MRD can trigger a new treatment much earlier than a radiological relapse.
Whether it is selecting patients for trial enrollment based on MRD status, using MRD as an exploratory endpoint or surrogate endpoint. Our test can help you to design better trials.
Our MRD assay allows you to understand how well patients are responding to the treatment you are testing with unprecedented sensitivity and specificity. While we do not aim to substitute imaging for response assessment, the depth of response to a given treatment can be better understood using our MRD test.
With our test, you can see the emergence of potential resistance mutations without another biopsy. This can help you to understand why a treatment is working or not working.
Here are some publications from our early development showing applications in Hodgkin Lymphoma and CNS Lymphoma.
Entirely noninvasive outcome prediction in central nervous system lymphomas using circulating tumor DNA. Blood (2024) 143 (6): 522–534.
(LINK: https://doi.org/10.1182/blood.2023022020 )
In-depth cell-free DNA sequencing reveals genomic landscape of Hodgkin’s lymphoma and facilitates ultrasensitive residual disease detection. Med (2021) 2 (10), 1171-1194.
(LINK: https://doi.org/10.1016/j.medj.2021.09.002 )
Whether you are working at an academic institution or in industry, if you plan to sequence cell-free DNA and analyze circulating tumor DNA please get in contact with us. We will work with you to design a project for your needs.
Our standard assays can be used for genotyping, MRD and relapse detection. Bespoke features can be added for individual projects.